Article
Protective effect of green tea against benzo[a]pyrene-induced mutations in the liver of Big Blue transgenic mice.
Mutation research - 1 Sept 2001
Jiang T, Glickman B W, de Boer J G
Abstract excerpt
We assessed the ability of green tea to protect against benzo[a]pyrene (B[a]P)-induced mutations in the liver of lacI transgenic male C57BL/6 Big Blue mice. The mice were given a 2% Japanese green tea hot water extract as their sole source of drinking water for 10 weeks. After 7 weeks, they received a total dose of 150 mg/kg B[a]P. Treatment with B[a]P resulted in a two-fold higher lacI mutant frequency than the...
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