Article
A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.
The Journal of biological chemistry - 1 Jul 2005
Roy Sanjit K, Shuman Jon D, Platanias Leonidas C, Shapiro Paul S, Reddy Sekhar P M, Johnson Peter F, Kalvakolanu Dhananjaya V
Abstract excerpt
Transcription factor CCAAT/enhancer-binding protein-beta (C/EBP-beta) regulates a variety of cellular functions in response to exogenous stimuli. We have reported earlier that C/EBP-beta induces gene transcription through a novel interferon (IFN)-response element called gamma-IFN-activated transcriptional element. We show here that IFN-gamma-induced, C/EBP-beta/gamma-IFN-activated transcriptional...
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