Article
The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma.
The Journal of biological chemistry - 9 May 2008
Li Hui, Gade Padmaja, Nallar Shreeram C, Raha Abhijit, Roy Sanjit K, Karra Sreenivasu, Reddy Janardan K, Reddy Sekhar P, Kalvakolanu Dhananjaya V
Abstract excerpt
Transcription factor CCAAT/enhancer-binding protein (C/EBP)-beta is crucial for regulating transcription of genes involved in a number of diverse cellular processes, including those involved in some cytokine-induced responses. However, the mechanisms that contribute to its diverse transcriptional activity are not yet fully understood. To gain an understanding into its mechanisms of action, we took a proteomic...
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