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Article

ERK1 and ERK2 activate CCAAAT/enhancer-binding protein-beta-dependent gene transcription in response to interferon-gamma.

The Journal of biological chemistry - 5 Jan 2001

Hu J, Roy S K, Shapiro P S, Rodig S R, Reddy S P, Platanias L C, Schreiber R D, Kalvakolanu D V

Abstract excerpt

Interferons (IFNs) regulate the expression of a number of cellular genes by activating the JAK-STAT pathway. We have recently discovered that CCAAAT/enhancer-binding protein-beta (C/EBP-beta) induces gene transcription through a novel IFN response element called the gamma-IFN-activated transcriptional element (Roy, S. K., Wachira, S. J., Weihua, X., Hu, J., and Kalvakolanu, D. V. (2000) J. Biol. Chem. 275,...

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Source

Identifiers

PMID: 10995751
DOI: 10.1074/jbc.M004885200

Genes

EBP
JAK1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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