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Article

Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.

The Journal of biological chemistry - 25 May 1992

Wilson K P, Malcolm B A, Matthews B W

Abstract excerpt

High resolution crystal structures have been determined for six chicken-type lysozymes that were constructed to investigate putative intermediates in the evolution of the lysozymes of modern game birds (Malcolm, B. A., Wilson, K. P., Matthews, B. W., Kirsch, J. F., and Wilson, A. C. (1990) Nature 345, 86-89). The amino acid replacements include Thr-40----Ser, Ile-55----Val, and Ser-91----Thr, as well as...

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PMID: 1587860

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