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Article

Importance of surrounding residues for protein stability of partially buried mutations.

Journal of biomolecular structure & dynamics - 1 Oct 2000

Gromiha M M, Oobatake M, Kono H, Uedaira H, Sarai A

Abstract excerpt

For understanding the factors influencing protein stability, we have analyzed the relationship between changes in protein stability caused by partially buried mutations and changes in 48 physico-chemical, energetic and conformational properties of amino acid residues. Multiple regression equations were derived to predict the stability of protein mutants and the efficiency of the method has been verified with both...

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PMID: 11089649
DOI: 10.1080/07391102.2000.10506666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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