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Article

Histone deacetylase 5 represses the transcription of cyclin D3.

Journal of cellular biochemistry - 15 Aug 2008

Roy Sangita, Shor Audrey C, Bagui Tapan K, Seto Edward, Pledger W Jackson

Abstract excerpt

Histone deacetylases (HDACs) modulate the transcription of a subset of genes by various means. HDAC5 is a class II HDAC whose subcellular location is signal-dependent. At present, its known gene targets are few in number. Here we identify a new HDAC5 target: the gene encoding the cell cycle-regulatory protein cyclin D3. When overexpressed in Balb/c-3T3 cells or mouse embryo fibroblasts, HDAC5 substantially...

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Source

Identifiers

PMID: 18404677
DOI: 10.1002/jcb.21771

Genes

HDAC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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