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Article

Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells.

The EMBO journal - 20 May 2009

Cho Sungyoo, Schroeder Sebastian, Kaehlcke Katrin, Kwon Hye-Sook, Pedal Angelika, Herker Eva, Schnoelzer Martina, Ott Melanie

Abstract excerpt

The elongation competence of the RNA polymerase II complex is critically dependent on the positive transcription elongation factor b (P-TEFb). P-TEFb exists in two forms in cells, an active form composed of cyclin T1 and CDK9 and an inactive form, in which cyclin T1/CDK9 is sequestered by Hexim1...

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Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Binding

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Share to tat Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 19387490
DOI: 10.1038/emboj.2009.99
PMCID: PMC2688543

Genes

CDK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19387490-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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