Article
The F-box protein Met30 is required for multiple steps in the budding yeast cell cycle.
Molecular and cellular biology - 1 May 2005
Su Ning Yuan, Flick Karin, Kaiser Peter
Abstract excerpt
The Saccharomyces cerevisiae ubiquitin ligase SCF(Met30) is essential for cell cycle progression. To identify and characterize SCF(Met30)-dependent cell cycle steps, we used temperature-sensitive met30 mutants in cell cycle synchrony experiments. These experiments revealed a requirement for Met30 during both G(1)/S transition and M phase, while progression through S phase was unaffected by loss of Met30 function....
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