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Article

Jumonji regulates cardiomyocyte proliferation via interaction with retinoblastoma protein.

The Journal of biological chemistry - 2 Sept 2005

Jung Jooyoung, Kim Tae-Gyun, Lyons Gary E, Kim Hyeong-Reh C, Lee Youngsook

Abstract excerpt

Jumonji (JMJ) can function as a transcriptional repressor and plays critical roles in embryonic development including heart development in mice. Although JMJ has been suggested to play a role in cell growth, the molecular mechanisms have not been resolved. The present data demonstrate that JMJ interacts with the retinoblastoma protein (Rb), one of the master regulatory genes of cell cycle. JMJ potentiates the...

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Identifiers

PMID: 15870077
DOI: 10.1074/jbc.M414482200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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