Article
Generation of a conditional null allele of jumonji.
Genesis (New York, N.Y. : 2000) - 1 Sept 2006
Mysliwiec Matthew R, Chen Junqin, Powers Patricia A, Bartley Christopher R, Schneider Michael D, Lee Youngsook
Abstract excerpt
The jumonji (jmj) gene plays important roles in multiple organ development in mouse, including cardiovascular development. Since JMJ is expressed widely during mouse development, it is essential that conditional knockout approaches be employed to ablate JMJ in a tissue-specific manner to identify the cell lineage specific roles of JMJ. In this report, we describe the establishment of a jmj conditional null allele...
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