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Article

Meis1 regulates postnatal cardiomyocyte cell cycle arrest.

Nature - 9 May 2013

Mahmoud Ahmed I, Kocabas Fatih, Muralidhar Shalini A, Kimura Wataru, Koura Ahmed S, Thet Suwannee, Porrello Enzo R, Sadek Hesham A

Abstract excerpt

The neonatal mammalian heart is capable of substantial regeneration following injury through cardiomyocyte proliferation. However, this regenerative capacity is lost by postnatal day 7 and the mechanisms of cardiomyocyte cell cycle arrest remain unclear. The homeodomain transcription factor Meis1 is required for normal cardiac development but its role in cardiomyocytes is unknown. Here we identify Meis1 as a...

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Identifiers

PMID: 23594737
DOI: 10.1038/nature12054
PMCID: PMC4159712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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