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Article

Genetic and other sources of variation in the activity of serum paraoxonase/diazoxonase in humans: consequences for risk from exposure to diazinon.

Pharmacogenetics and genomics - 1 Jan 2005

O'Leary Karen A, Edwards Robert J, Town Margaret M, Boobis Alan R

Abstract excerpt

Diazinon is the only organophosphorus insecticide that is currently approved for use in sheep dip in the UK. Reports that some individuals may be genetically more susceptible to possible chronic adverse health effects, due to variations in PON1 activity, are complicated by the reliability of activity measurements. In the present study, the influence of three polymorphisms of PON1 on serum diazoxonase activity was...

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PMID: 15864126
DOI: 10.1097/01213011-200501000-00008

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PON1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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