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Article

Determination of paraoxonase (PON1) status requires more than genotyping.

Pharmacogenetics - 1 Dec 1999

Richter R J, Furlong C E

Abstract excerpt

Human serum paraoxonase (PON1) is associated with high density lipoprotein (HDL) particles. This enzyme is involved in the metabolism of oxidized lipids and also plays a major role in the metabolism and detoxication of insecticides processed through the cytochrome P450/PON1 pathway. An Arg/Gln (R/Q) substitution at position 192 determines a substrate dependent activity polymorphism. In addition to the effect of...

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Source

Identifiers

PMID: 10634137

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Determination of paraoxonase (PON1) status requires more than genotyping.PMID 10634137Read ↗

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