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Article

Determination of paraoxonase 1 status and genotypes at specific polymorphic sites.

Current protocols in toxicology - 1 May 2004

Richter Rebecca J, Jampsa Rachel L, Jarvik Gail P, Costa Lucio G, Furlong Clement E

Abstract excerpt

The procedures for determining paraoxonase (PON1) status and for determining PON1 genotypes for polymorphisms in coding and important regulatory regions are described. PON1 status is determined by a functional two-substrate analysis of plasma PON1 activities. Differences in catalytic efficiency of the PON1₁₉₂Q and PON1₁₉₂R alloforms result in the clear separation of all three phenotypes at position 192 (Q/Q, Q/R,...

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Source

Identifiers

PMID: 20945303
DOI: 10.1002/0471140856.tx0412s19

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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