Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-environmental interactions and organophosphate toxicity.

Toxicology - 30 Dec 2010

Povey Andrew C

Abstract excerpt

Organophosphates (OPs) are an important class of insecticides that in the UK have been widely used for treating sheep for ectoparasites as well as in other sectors of the farming industry. Health problems associated with acute OP toxicity are well defined but, ill-health induced by chronic exposures to OPs remains controversial. A substantial number of sheep farmers complain of chronic ill-health which they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Husbandry
Share to Aryldialkylphosphatase
Share to Environmental Pollutants

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insecticides

Share to Occupational Exposure

Share to Organophosphorus Compounds

Share to Sheep Diseases

Source

Identifiers

PMID: 20156521
DOI: 10.1016/j.tox.2010.02.007

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-environmental interactions and organophosphate toxicity.PMID 20156521Read ↗

Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep.Semantic proximity Read ↗

GST CYP and PON1 polymorphisms in farmers attributing ill health to organophosphate-containing sheep dip.Semantic proximity Read ↗

Genetic and other sources of variation in the activity of serum paraoxonase/diazoxonase in humans: consequences for risk from exposure to diazinon.Semantic proximity Read ↗

Paraoxonase polymorphisms and self-reported chronic ill-health in farmers dipping sheep.Semantic proximity Read ↗

Genetic variability in the cytochrome P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds.Semantic proximity Read ↗

The role of PON1 and CYP2D6 genes in susceptibility to organophosphorus chronic intoxication in Egyptian patients.Semantic proximity Read ↗

CYP/PON genetic variations as determinant of organophosphate pesticides toxicity.Semantic proximity Read ↗

The toxicity of mixtures of specific organophosphate compounds is modulated by paraoxonase 1 status.Semantic proximity Read ↗

Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity.Semantic proximity Read ↗

'Dippers' flu' and its relationship to PON1 polymorphisms.Semantic proximity Read ↗

Polymorphisms of pesticide-metabolizing genes in children living in intensive farming communities.Semantic proximity Read ↗

Association between human paraoxonase gene polymorphism and chronic symptoms in pesticide-exposed workers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.