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Article

Genetic variations of the A13/A14 repeat located within the EGFR 3' untranslated region have no oncogenic effect in patients with colorectal cancer.

BMC cancer - 8 Apr 2013

Sarafan-Vasseur Nasrin, Sefrioui David, Tougeron David, Lamy Aude, Blanchard France, Le Pessot Florence, Di Fiore Frédéric, Michel Pierre, Bézieau Stéphane, Latouche Jean-Baptiste, Frebourg Thierry, Sesboüé Richard

Abstract excerpt

BACKGROUND: The EGFR 3' untranslated region (UTR) harbors a polyadenine repeat which is polymorphic (A13/A14) and undergoes somatic deletions in microsatellite instability (MSI) colorectal cancer (CRC). These mutations could be oncogenic in colorectal tissue since they were shown to result into i...

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Identifiers

PMID: 23565769
DOI: 10.1186/1471-2407-13-183
PMCID: PMC3626788

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23565769-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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