Article
Analysis of the proepicardium-epicardium transition during the malformation of the RXRalpha-/- epicardium.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2005
Jenkins Shantae J, Hutson D Renée, Kubalak Steven W
Abstract excerpt
The epicardium of the heart originates from a cluster of mesothelial-derived cells that develop beneath the sinus venosus in the embryonic day (E) 9.0-9.5 mouse. The subsequent proepicardium-epicardium transition that forms the epicardial layer of epithelial cells covering the myocardial surface is nearly complete by E10.0-E10.5 and results in a fully covered heart by E11.0. In this study, we show that an...
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