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The ontogeny, activation and function of the epicardium during heart development and regeneration

28 Mar 2018

Abstract excerpt

The epicardium plays a key role during cardiac development, homeostasis and repair, and has thus emerged as a potential target in the treatment of cardiovascular disease. However, therapeutically manipulating the epicardium and epicardium-derived cells (EPDCs) requires insights into their developmental origin and the mechanisms driving their activation, recruitment and contribution to both the embryonic and adult...

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Identifiers

PMID: 29592950
DOI: 10.1242/dev.155994

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