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Article

Identification of 2 major loci linked to autoimmune hemolytic anemia in NZB mice.

Blood - 15 Aug 2005

Kikuchi Shuichi, Amano Hirofumi, Amano Eri, Fossati-Jimack Liliane, Santiago-Raber Marie-Laure, Moll Thomas, Ida Akinori, Kotzin Brian L, Izui Shozo

Abstract excerpt

Using a cohort of C57BL/6 (B6) x (NZB x B6)F1 backcross male mice bearing the Yaa (Y-linked autoimmune acceleration) mutation, we mapped and characterized the NZB-derived susceptibility loci predisposing to the development of autoimmune hemolytic anemia (AHA). Our analysis identified 2 major loci on NZB chromosome 7 and chromosome 1 linked with Coombs antierythrocyte autoantibody production, and their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred NZB

Source

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Identifiers

PMID: 15860660
DOI: 10.1182/blood-2005-02-0558
PMCID: PMC1895197

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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