Article
Directed evolution: selecting today's biocatalysts.
Biomolecular engineering - 1 Jun 2005
Otten Linda G, Quax Wim J
Abstract excerpt
Directed evolution has become a full-grown tool in molecular biology nowadays. The methods that are involved in creating a mutant library are extensive and can be divided into several categories according to their basic ideas. Furthermore, both screening and selection can be used to target the enzyme towards the desired direction. Nowadays, this technique is broadly used in two major applications: (industrial)...
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