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Article

Advances in laboratory evolution of enzymes.

Current opinion in chemical biology - 1 Apr 2008

Bershtein Shimon, Tawfik Dan S

Abstract excerpt

We address recent developments in the area of laboratory, or directed evolution, with a focus on enzymes and on new methodologies of generic potential. We survey three main areas: (i) library making techniques, including the application of computational and rational methods for library design; (ii) screening and selection techniques, including recent applications of enzyme screening by FACS (fluorescence...

Topics

Directed Molecular Evolution
Enzymes
Flow Cytometry
Gene Library
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18284924
DOI: 10.1016/j.cbpa.2008.01.027

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