Article
RNAi-mediated allelic trans-interaction at the imprinted Rtl1/Peg11 locus.
Current biology : CB - 26 Apr 2005
Davis Erica, Caiment Florian, Tordoir Xavier, Cavaillé Jérôme, Ferguson-Smith Anne, Cockett Noelle, Georges Michel, Charlier Carole
Abstract excerpt
The Dlk1-Gtl2 imprinted domain, encompassing the callipyge (CLPG) locus in sheep, has recently been shown to harbor a large number of maternally expressed miRNA genes [1, 2]. Two of these (mir127 and mir136) are processed from a transcript (antiPeg11) that is antisense to Rtl1/Peg11, a paternally expressed intronless gene with homology to the gag and pol polyproteins of Sushi-like retroelements [3]. We herein...
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