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Article

Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes.

Development (Cambridge, England) - 2 Sept 2020

Kitazawa Moe, Hayashi Shinichiro, Imamura Michihiro, Takeda Shin'ichi, Oishi Yumiko, Kaneko-Ishino Tomoko, Ishino Fumitoshi

Abstract excerpt

Temple and Kagami-Ogata syndromes are genomic imprinting diseases caused by maternal and paternal duplication of human chromosome 14, respectively. They exhibit different postnatal muscle-related symptoms as well as prenatal placental problems. Using the mouse models for these syndromes, it has been demonstrated that retrotransposon gag like 1 [Rtl1, also known as paternally expressed 11 (Peg11)] located in the...

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Identifiers

PMID: 32878913
DOI: 10.1242/dev.185918
PMCID: PMC7490516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes.PMID 32878913Read ↗

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