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Article

A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development.

Development (Cambridge, England) - 15 Jul 2015

Ito Mitsuteru, Sferruzzi-Perri Amanda N, Edwards Carol A, Adalsteinsson Bjorn T, Allen Sarah E, Loo Tsui-Han, Kitazawa Moe, Kaneko-Ishino Tomoko, Ishino Fumitoshi, Stewart Colin L, Ferguson-Smith Anne C

Abstract excerpt

The paternally expressed imprinted retrotransposon-like 1 (Rtl1) is a retrotransposon-derived gene that has evolved a function in eutherian placentation. Seven miRNAs, including miR-127, are processed from a maternally expressed antisense Rtl1 transcript (Rtl1as) and regulate Rtl1 levels through RNAi-mediated post-transcriptional degradation. To determine the relative functional role of Rtl1as miRNAs in Rtl1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26138477
DOI: 10.1242/dev.121996
PMCID: PMC4510861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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