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Article

Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2.

Nucleic acids research - 1 Feb 2012

MacIsaac Julia L, Bogutz Aaron B, Morrissy A Sorana, Lefebvre Louis

Abstract excerpt

The gene Mest (also known as Peg1) is regulated by genomic imprinting in the mouse and only the paternal allele is active for transcription. MEST is similarly imprinted in humans, where it is a candidate for the growth retardation Silver-Russell syndrome. The MEST protein belongs to an ancient family of hydrolases but its function is still unknown. It is highly conserved in vertebrates although imprinted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22053079
DOI: 10.1093/nar/gkr871
PMCID: PMC3287194

Genes

MEST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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