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Article

E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions.

The Journal of pathology - 1 Jul 2005

Hubert Pascale, Caberg Jean-Hubert, Gilles Christine, Bousarghin Latifa, Franzen-Detrooz Elizabeth, Boniver Jacques, Delvenne Philippe

Abstract excerpt

Although human papillomavirus (HPV) DNA is detected in the majority of squamous intraepithelial lesions (SILs) and squamous cell carcinomas (SCCs) of the uterine cervix, the persistence and progression of cervical lesions suggest that viral antigens are not adequately presented to the immune system. This hypothesis is reinforced by the observation that most SILs show quantitative and functional alterations of...

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Identifiers

PMID: 15852499
DOI: 10.1002/path.1771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions.PMID 15852499Read ↗

Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytesSemantic proximity Read ↗

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The antigen-presenting environment in normal and human papillomavirus (HPV)-related premalignant cervical epitheliumSemantic proximity Read ↗

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