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Article

The antigen-presenting environment in normal and human papillomavirus (HPV)-related premalignant cervical epithelium

1 Apr 1999

Abstract excerpt

The activation of HPV-specific T cells within the cervical microenvironment is likely to play an important part in the natural history of cervical intraepithelial neoplasia (CIN). The extent and the type of T cell activation will depend critically on the expression of MHC, costimulatory cell surface molecules and cytokines by keratinocytes and Langerhans cells within the cervical lesion. Expression of MHC class...

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PMID: 10209502
DOI: 10.1046/j.1365-2249.1999.00826.x

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