Article
Association of HLA class I and class II polymorphisms with age-related macular degeneration.
Investigative ophthalmology & visual science - 1 May 2005
Goverdhan Srini V, Howell Martin W, Mullins Robert F, Osmond Clive, Hodgkins Peter R, Self James, Avery Kim, Lotery Andrew J
Abstract excerpt
PURPOSE: To evaluate whether HLA genotypes are associated with age-related macular degeneration (AMD). METHODS: HLA class I-A, -B, and -Cw and class II DRB1 and DQB1 principal allele groups were genotyped in two stages: initially for principal allele groups in a cohort of 100 AMD cases and 92 control subjects, and then, in the next 100 cases and controls from the same cohort, for alleles or allele groups with P <...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.