Article
Association of age-related macular degeneration with polymorphisms in vascular endothelial growth factor and its receptor.
Ophthalmology - 1 Sept 2010
Galan Alessandro, Ferlin Alberto, Caretti Luigi, Buson Genny, Sato Giovanni, Frigo Anna Chiara, Foresta Carlo
Abstract excerpt
OBJECTIVE: To analyze the association between age-related macular degeneration (AMD) and polymorphisms in vascular endothelial growth factor (VEGF) and VEGF receptor KDR gene polymorphisms. A complex, multifactorial disease in which genetic and environmental factors interact, AMD is the leading cause of blindness in the elderly. Vascular endothelial growth factor (VEGF), a key regulator of angiogenesis, is...
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