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Article

Age-related macular degeneration is associated with the HLA-Cw*0701 Genotype and the natural killer cell receptor AA haplotype.

Investigative ophthalmology & visual science - 1 Nov 2008

Goverdhan Srinivas V, Khakoo Salim I, Gaston Hannah, Chen Xiaoli, Lotery Andrew J

Abstract excerpt

PURPOSE: To determine the association of human leukocyte antigen (HLA) C and its cognate killer cell immunoglobulin-like receptor (KIR) ligands with age-related macular degeneration (AMD). METHODS: HLA class I allele groups including the HLA-C principal alleles were genotyped in a cohort of 104 AMD cases and 93 controls by using the PCR-SSP (sequence-specific primers) METHOD: This cohort was then genotyped for 16...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18515573
DOI: 10.1167/iovs.08-1837
PMCID: PMC5989921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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