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Article

HLA class II genotypes are not associated with age related macular degeneration in a case-control, population-based study.

Human immunology - 1 Mar 2015

Pappas Derek, Hollenbach Jill, Coleman Anne L, Gorin Michael B, Yu Fe, Williams Kevin, Noble Janelle, Tranah Gregory J

Abstract excerpt

Multiple lines of evidence support an immunologic basis and genetic disposition for the development of age-related macular degeneration (AMD). Comprehensive human leukocyte antigens (HLA) class II typing at four loci (DRB1, DQA1, DQB1, and DPB1) was assessed using next generation sequencing methods and tested for association with age-related macular degeneration (AMD) in a case-control study of 456 AMD cases and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25665771
DOI: 10.1016/j.humimm.2015.01.010
PMCID: PMC4476503

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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