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Article

Common coding variants in the HLA-DQB1 region confer susceptibility to age-related macular degeneration.

European journal of human genetics : EJHG - 1 Jul 2016

Jorgenson Eric, Melles Ronald B, Hoffmann Thomas J, Jia Xiaoming, Sakoda Lori C, Kvale Mark N, Banda Yambazi, Schaefer Catherine, Risch Neil, Shen Ling

Abstract excerpt

Age-related macular degeneration (AMD) risk variants in the complement system point to the important role of immune response and inflammation in the pathogenesis of AMD. Although the human leukocyte antigen (HLA) region has a central role in regulating immune response, previous studies of genetic variation in HLA genes and AMD have been limited by sample size or incomplete coverage of the HLA region by...

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Identifiers

PMID: 26733291
DOI: 10.1038/ejhg.2015.247
PMCID: PMC5070898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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