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Article

Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study.

PloS one - 1 Jan 2013

Ricci Federico, Staurenghi Giovanni, Lepre Tiziana, Missiroli Filippo, Zampatti Stefania, Cascella Raffaella, Borgiani Paola, Marsella Luigi Tonino, Eandi Chiara Maria, Cusumano Andrea, Novelli Giuseppe, Giardina Emiliano

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic and environmental factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23840568
DOI: 10.1371/journal.pone.0066978
PMCID: PMC3686762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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