Article
Frequencies of human leukocyte antigen alleles and haplotypes among Japanese patients with age-related macular degeneration.
Japanese journal of ophthalmology - 1 Sept 2018
Takagi Seiji, Mandai Michiko, Hirami Yasuhiko, Sugita Sunao, Takahashi Masayo, Kurimoto Yasuo
Abstract excerpt
PURPOSE: Stem cell therapy is a potential treatment for retinal disorders. We are currently exploring treating HLA matched patients of age-related macular degeneration (AMD) by using allogenic retinal pigment epithelium cells derived from induced pluripotent stem cells (iPS-RPE) from human leukocyte antigen (HLA) homozygote donors. The purpose of this study was to investigate the frequency of HLA class I and II...
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