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Article

The epsilon2 and epsilon4 alleles of the apolipoprotein gene are associated with age-related macular degeneration.

Investigative ophthalmology & visual science - 1 May 2004

Baird Paul N, Guida Elizabeth, Chu Diep T, Vu Hien T V, Guymer Robyn H

Abstract excerpt

PURPOSE: To date, of all the genes studied in relation to age-related macular degeneration (AMD), the alleles of the apolipoprotein (apoE) gene have been the most consistently associated with disease. However, not all apoE studies have found an association, and among these the associations differ. The current study was conducted to investigate further the association of this gene in AMD. METHODS: Three hundred...

Topics

Aged
Alleles
Apolipoprotein E2
Apolipoprotein E4
Apolipoproteins E
DNA
Female
Genotype
Humans
Macular Degeneration
Male
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15111582
DOI: 10.1167/iovs.03-1121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15111582-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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