Article
TNF-857T, a genetic risk marker for acute anterior uveitis.
Investigative ophthalmology & visual science - 1 May 2005
Kuo Ni-Wen, Lympany Penny A, Menezo Victor, Lagan Anna L, John Sally, Yeo Tun Kuan, Liyanage Sidath, du Bois Roland M, Welsh Kenneth I, Lightman Susan
Abstract excerpt
PURPOSE: To determine the association between 17 single nucleotide polymorphisms (SNPs) of tumor necrosis factor-alpha, lymphotoxin-alpha, and the TNF-receptors genes (TNF, LTA, and TNFRSF1A and -B) and idiopathic acute anterior uveitis (IAU) and to investigate their association with HLA-B27 and/or the development of visually significant complications. METHODS: Ninety-eight white patients in the United Kingdom...
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