Article
Tumor necrosis factor polymorphisms associated with tumor necrosis factor production influence the risk of idiopathic intermediate uveitis.
Molecular vision - 1 Jan 2013
Atan Denize, Heissigerova Jarka, Kuffová Lucia, Hogan Aideen, Kilmartin Dara J, Forrester John V, Bidwell Jeff L, Dick Andrew D, Churchill Amanda J
Abstract excerpt
PURPOSE: Idiopathic intermediate uveitis (IIU) is a potentially sight-threatening inflammatory disorder with well-defined anatomic diagnostic criteria. It is often associated with multiple sclerosis, and both conditions are linked to HLA-DRB1*15. Previously, we have shown that non-infectious uveitis (NIU) is associated with interleukin 10 (IL10) polymorphisms, IL10-2849A (rs6703630), IL10+434T (rs2222202), and...
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