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Article

[TNF-alfa (-857C/T) polymorphism in open angle glaucoma in Romania -- results of a pilot study].

Oftalmologia (Bucharest, Romania : 1990) - 1 Jan 2013

Simionescu Ruxandra, Voinea Liliana, Cornăţeanu Roxana Sfrenţ

Abstract excerpt

UNLABELLED: Primary open angle glaucoma is a progressive optic neuropathy with multiple causative factors including genetic immune disregulation. TNF-alfa has pro-apoptotic effects on the retinal ganglion cells, thus being directly involved in the neurodegeneration of the optic nerve head. Our purpose was to investigate the influence on susceptibility and/or clinical and characteristics of TNF-alfa promoter...

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PMID: 24844040

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TNF

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