Article
Association of Genetic Variations in TNFSF15 With Acute Anterior Uveitis in Chinese Han.
Investigative ophthalmology & visual science - 1 Jul 2015
Li Hua, Hou Shengping, Yu Hongsong, Zheng Minming, Zhang Lijun, Zhang Jun, Zhang Qi, Cao Qingfeng, Yuan Gangxiang, Kijlstra Aize, Yang Peizeng
Abstract excerpt
PURPOSE: T cells play an important role in the pathogenesis of uveitis. Recent studies have indicated that the TNFSF15 gene that encodes the TL1A protein can regulate the differentiation and activation of T cells. TNFSF15 gene polymorphisms have been found to be associated with several autoimmune disorders. A possible association of TNFSF15 with acute anterior uveitis (AAU) has not yet been reported and was...
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