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Article

Genetic susceptibility to acquired long QT syndrome: pharmacologic challenge in first-degree relatives.

Heart rhythm - 1 Feb 2005

Kannankeril Prince J, Roden Dan M, Norris Kris J, Whalen S Patrick, George Alfred L, Murray Katherine T

Abstract excerpt

OBJECTIVES: The purpose of this study was to test for a genetic component to risk for acquired long QT syndrome (LQTS). BACKGROUND: Many drugs prolong the QT interval, and some patients develop excessive QT prolongation and occasionally torsades de pointes-the acquired LQTS. Similarities between the acquired and congenital forms of the long QT syndrome suggest genetic factors modulate susceptibility. METHODS:...

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Identifiers

PMID: 15851285
DOI: 10.1016/j.hrthm.2004.10.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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