Article
Evidence for a cardiac ion channel mutation underlying drug-induced QT prolongation and life-threatening arrhythmias.
Journal of cardiovascular electrophysiology - 1 Jun 2000
Napolitano C, Schwartz P J, Brown A M, Ronchetti E, Bianchi L, Pinnavaia A, Acquaro G, Priori S G
Abstract excerpt
The aim of this study was to test the hypothesis that some cases of drug-induced arrhythmias depend on genetic predisposition. Excessive prolongation of the QT interval and life-threatening arrhythmias (torsades de pointes or ventricular fibrillation) may occur in response to a variety of cardiac...
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