Article
Long QT syndrome: reduced repolarization reserve and the genetic link.
Journal of internal medicine - 1 Jan 2006
Roden D M
Abstract excerpt
Marked QT prolongation and torsades de pointes can occur not only in the congenital long QT syndromes (LQTSs) but also as a consequence of environmental stimuli, notably administration of certain drugs. A key feature of this 'acquired' form of the LQTS has been its unpredictable nature. That is, although risk factors have been identified in series of patients, they have not been terribly useful in addressing risk...
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