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Article

Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.

Heart rhythm - 1 May 2007

Lehtonen Annukka, Fodstad Heidi, Laitinen-Forsblom Päivi, Toivonen Lauri, Kontula Kimmo, Swan Heikki

Abstract excerpt

BACKGROUND: Pathophysiologically significant ion-channel mutations have been detected in only a minority of cases of acquired long QT syndrome (LQTS). OBJECTIVE: The aim of this study was to clarify the putative role of subclinical inherited LQTS in drug-associated torsades de pointes (TdP) and to assess the concomitant proarrhythmic factors. METHODS: We evaluated 16 consecutive cases with documented,...

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Source

Identifiers

PMID: 17467628
DOI: 10.1016/j.hrthm.2007.01.019

Genes

KCNQ1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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