Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural characterization of the transmembrane and cytoplasmic domains of human CD4.

Biochimica et biophysica acta - 1 Dec 2007

Wittlich Marc, Koenig Bernd W, Hoffmann Silke, Willbold Dieter

Abstract excerpt

Cluster determinant 4 (CD4) is a type I transmembrane glycoprotein of 58 kDa. It consists of an extracellular domain of 370 amino acids, a short transmembrane region, and a cytoplasmic domain of 40 amino acids at the C-terminal end. We investigated the structure of the 62 C-terminal residues of CD4, comprising its transmembrane and cytoplasmic domains. The five cysteine residues of this region have been replaced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbon Isotopes
Share to CD4 Antigens
Share to Circular Dichroism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Immunodeficiency Virus Proteins

Share to Magnetic Resonance Spectroscopy

Share to Nitrogen Isotopes

Share to Protein Structure, Secondary

Share to Viral Regulatory and Accessory Proteins

Source

Identifiers

PMID: 18035040
DOI: 10.1016/j.bbamem.2007.10.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural characterization of the transmembrane and cytoplasmic domains of human CD4.PMID 18035040Read ↗

Recombinant production of the amino terminal cytoplasmic region of dengue virus non-structural protein 4A for structural studies.Semantic proximity Read ↗

CC2D1A is a regulator of ESCRT-III CHMP4B.Semantic proximity Read ↗

Dengue virus NS4A cytoplasmic domain binding to liposomes is sensitive to membrane curvature.Semantic proximity Read ↗

Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolutionSemantic proximity Read ↗

Multiple interests in structural models of DARC transmembrane protein.Semantic proximity Read ↗

The MHC-binding and gp120-binding functions of CD4 are separable.Semantic proximity Read ↗

Towards the NMR solution Structure and the Dynamics of the C-terminal Region of APOL1 and its G1, G2 Variants with a Membrane MimeticSemantic proximity Read ↗

Structural organization and interactions of transmembrane domains in tetraspanin proteins.Semantic proximity Read ↗

Purification of native CCL7 and its functional interaction with selected chemokine receptorsSemantic proximity Read ↗

Functional manipulation of a calcium-binding protein from Entamoeba histolytica guided by paramagnetic NMR.Semantic proximity Read ↗

The solution structure of the adhesion protein Bd37 from Babesia divergens reveals structural homology with eukaryotic proteins involved in membrane trafficking.Semantic proximity Read ↗

NMR structural studies of human cystatin C dimers and monomers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.