Article
Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder.
Pharmacopsychiatry - 1 Jan 2009
Rybakowski J K, Dmitrzak-Weglarz M, Suwalska A, Leszczynska-Rodziewicz A, Hauser J
Abstract excerpt
BACKGROUND: Previously, we have found an association between the -48 A/G polymorphism of the dopamine receptor D1 (DRD1) gene and bipolar disorder. The aim of the present study was to investigate a possible association of this polymorphism with the quality of the prophylactic lithium response in bipolar patients. METHODS: Ninety-two patients (39 male, 53 female), aged 30-77 (mean: 54 years) were studied. They...
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