Article
Acute antipyschotic efficacy and side effects in schizophrenia: association with serotonin transporter promoter genotypes.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2008
Dolzan Vita, Serretti Alessandro, Mandelli Laura, Koprivsek Jure, Kastelic Matej, Plesnicar Blanka Kores
Abstract excerpt
BACKGROUND: The serotonin transporter (5-HTT) plays an important role in serotonergic neurotransmission. In the present study, we investigated the effects of the 44 bp insertion/deletion polymorphism in the promoter region of 5-HTT gene (5-HTTLPR) on symptomatology of psychosis and clinical response to antipsychotic drugs. METHODS: In total 56 patients acutely treated with haloperidol or risperidone either for...
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