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Article

Association studies of 5-HT2A and 5-HT2C serotonin receptor gene polymorphisms with prophylactic lithium response in bipolar patients.

Pharmacological reports : PR - 1 Jan 2000

Dmitrzak-Weglarz Monika, Rybakowski Janusz K, Suwalska Aleksandra, Słopień Agnieszka, Czerski Piotr M, Leszczyńska-Rodziewicz Anna, Hauser Joanna

Abstract excerpt

Lithium is one of the most commonly used drugs in the prophylaxis and treatment of bipolar disorder. The mechanisms of mood stabilization by lithium incorporate its effect on serotonergic neurotransmission. This paper investigates a relationship between response to lithium prophylaxis and polymorphisms in two genes: T102C of 5-HT2A receptor and G68C (Cys23Ser) of 5-HT2C serotonin receptor gene. Genotypes were...

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PMID: 16382194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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