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Article

The serine/threonine kinases SGK1, 3 and PKB stimulate the amino acid transporter ASCT2.

Biochemical and biophysical research communications - 27 May 2005

Palmada Monica, Speil Andreas, Jeyaraj Sankarganesh, Böhmer Christoph, Lang Florian

Abstract excerpt

The human Na(+)-dependent neutral amino acid transporter type 2 (hASCT2/SLC1A5) plays an important role in the transport of neutral amino acids in epithelial cells. The serine and threonine kinases SGK1-3 and protein kinase B have been implicated in the regulation of several members of the SLC1 transporter family by enhancing their plasma membrane abundance. The present study explored whether those kinases...

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Source

Identifiers

PMID: 15845389
DOI: 10.1016/j.bbrc.2005.03.159

Genes

SGK1
SGK3
IGF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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