Article
Regulation of the human Na+-dependent glucose cotransporter hSGLT2.
American journal of physiology. Cell physiology - 1 Aug 2012
Ghezzi Chiara, Wright Ernest M
Abstract excerpt
The human Na(+)-glucose cotransporter SGLT2 is expressed mainly in the kidney proximal convoluted tubule where it is considered to be responsible for the bulk of glucose reabsorption. Phosphorylation profiling has revealed that SGLT2 exists in a phosphorylated state in the rat renal proximal tubule cortex, so we decided to investigate the regulation of human SGLT2 (hSGLT2) by protein kinases. hSGLT2 was expressed...
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